Table 3 Joint-effect analysis of APOL2, APOL3 and APOL6 for prognosis analysis in GSE14520 cohort.
Group | APOL2 | APOL3 | APOL6 | Prognosis | MST (Months) | Adjusted HR (95%CI) | Adjusted P value& |
|---|---|---|---|---|---|---|---|
Events/total | |||||||
RFS | |||||||
I | Low | Low | 47/71 | 23.0 | Reference | 0.018 | |
II | Low | High | 38/70 | 51.1 | 0.731 (0.469–1.139) | 0.166 | |
High | Low | ||||||
III | High | High | 31/71 | 59.5 | 0.509 (0.320–0.812) | 0.005 | |
1 | Low | Low | 49/72 | 19.6 | Reference | 0.004 | |
2 | Low | High | 36/68 | 51.6 | 0.607 (0.393–0.938) | 0.025 | |
High | Low | ||||||
3 | High | High | 31/72 | NA | 0.474 (0.299–0.751) | 0.002 | |
A | Low | Low | 50/77 | 22.8 | Reference | 0.007 | |
B | Low | High | 34/58 | 32.6 | 0.724 (0.464–1.130) | 0.155 | |
High | Low | ||||||
C | High | High | 32/77 | NA | 0.485 (0.308–0.763) | 0.002 | |
a | Low | Low | Low | 41/57 | 19.4 | Reference | 0.001 |
b | Low | High | Low | 23/49 | NA | 0.479 (0.285–0.807) | 0.006 |
Low | Low | High | |||||
High | Low | Low | |||||
c | High | High | Low | 31/49 | 36.6 | 0.676 (0.422–1.084) | 0.104 |
High | Low | High | |||||
Low | High | High | |||||
d | High | High | High | 21/57 | NA | 0.343 (0.200–0.591) | < 0.001 |
OS | |||||||
● | Low | Low | 39/77 | 51.6 | Reference | 0.015 | |
●● | Low | High | 24/58 | NA | 0.701 (0.418–1.176) | 0.179 | |
High | Low | ||||||
●●● | High | High | 19/77 | NA | 0.437 (0.248–0.770) | 0.004 |
