Figure 4
From: Metabolic brain imaging with glucosamine CEST MRI: in vivo characterization and first insights
1H‐decoupled 13C NMR spectra of pooled extracts from brains of mice (a) untreated (n=5), (b) 15 min after treatment with [UL‐13C] ‐GlcN·HCl (2 g/kg IV, n=5), (d) 30 minutes after treatment with [UL‐13C] ‐GlcN·HCl (2 g/kg IV, n=5), (f) 60 min after treatment with [UL‐13C] ‐GlcN·HCl (2 g/kg IV, n=5), and the (c,e,g) corresponding net* signal of GlcN and its metabolites in the brains, respectively (B0=11.7T, T=25°C, pH=7.4). *The green lines represent the difference between the treatment and the baseline.
