Table 2 Biomarker (spikes, HFO, spikes + HFO) and seizure outcome.

From: High frequency oscillations in relation to interictal spikes in predicting postsurgical seizure freedom

 

HFO

Spikes

Spikes + HFO

Sensitivity [%]

TP/(TP + FN)

57 [18 90]

71 [29 96]

67 [22 96]

Specificity [%]

TN/(TN + FP)

100 [75 100]

54 [25 81]

85 [55 98]

PPV [%]

TP/(TP + FP)

100 [40 100]

45 [17 77]

67 [22 96]

NPV [%]

TN/(TN + FN)

81 [54 96]

78 [40 97]

85 [55 98]

Accuracy [%]

(TP + TN)/N

85 [62 97]

60 [36 81]

79 [54 94]

  1. Values in brackets denote the 95% confidence interval. HFO are defined as fast ripples co-occurring with ripples. Abbreviations: FN False Negative, FP False Positive, NPV Negative Predictive Value, PPV Positive Predictive Value, TN True Negative, TP True Positive, N number of patients.
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