Figure 3 | Scientific Reports

Figure 3

From: A novel biomarker of MMP-cleaved cartilage intermediate layer protein-1 is elevated in patients with rheumatoid arthritis, ankylosing spondylitis and osteoarthritis

Figure 3

Levels of CILP-M in the discovery and validation cohort, together with receiver operating characteristic (ROC) curves. (A) CILP-M levels in the discovery cohort; (B) ROC curve analysis evaluating the ability of CILP-M to discriminate between healthy controls and RA//OA/AS respectively, in the discovery cohort. Data is shown as Tuckey plots; (C) CILP-M levels in the validation cohort; (D) ROC curve analysis evaluating the ability of CILP-M to discriminate between healthy controls and RA/AS respectively, in the validation cohort. Data was analysed using ANCOVA test (adjusting for age and gender in the validation cohort) and Area under the receiver operating characteristic curve (AUROC) analysis. Abbreviations: RA, rheumatoid arthritis; AS, ankylosing spondylitis; OA, osteoarthritis; AUC, Area Under the Curve. 

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