Figure 4 | Scientific Reports

Figure 4

From: A novel biomarker of MMP-cleaved cartilage intermediate layer protein-1 is elevated in patients with rheumatoid arthritis, ankylosing spondylitis and osteoarthritis

Figure 4

Subset analysis of CILP-M in patients with AS from the validation study. (A) CILP-M serum levels at baseline (week 0) and after treatment (12 weeks) in patients with AS (n = 42). Biomarker levels are presented in spaghetti plot with mean highlighted in bold. Paired t-test was performed; (B) CILP-M serum levels in BASDAI responders (n = 35) and non-responders (n = 16) to TNF inhibitor in patients with AS at baseline (week 0) and after 12 weeks. Data is shown as Tukey box plots. A linear mixed model was used.

Back to article page