Figure 2 | Scientific Reports

Figure 2

From: Hs27 fibroblast response to contact guidance cues

Figure 2

(a) A cell aspect ratio (\(\mathrm{\alpha }\)) for different topographic conditions. Each column represents three different cases: (from left to right) G2RN (\({{\text{G}}}_{{\text{w}}}=2\,\mathrm{ \mu m}\) and \({{\text{R}}}_{{\text{w}}}=\,\mathrm{N \mu m}\)), GNRN (\({{\text{G}}}_{{\text{w}}}={{\text{R}}}_{{\text{w}}}=\,\mathrm{N \mu m}\)), and GNR2 (\({{\text{G}}}_{{\text{w}}}=\,\mathrm{N \mu m}\) and \({{\text{R}}}_{{\text{w}}}=2\,\mathrm{ \mu m}\)). Each row indicates different groove depths: (from top to bottom) \({{\text{G}}}_{{\text{D}}}=330, 725,\,\mathrm{and}\,1000\,\mathrm{ nm}\) Cont. indicates a control experiment on a flat control substrate. (b) \({{{P}}}_{\overline{\mathrm{\alpha }}\ge 2 }\) is the percentage population of elongated cells (\(\overline{\mathrm{\alpha } }\ge 2\)) for (left to right) G2RN, GNRN, and GNR2, respectively.

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