Table 1 Characteristics of the 23 forensic aDMPs in blood.

From: Longitudinal changes and variation in human DNA methylation analysed with the Illumina MethylationEPIC BeadChip assay and their implications on forensic age prediction

CpG ID	Associated gene	GRCh38 chromo-somal position	R²	Age pattern	Age estimate¹	Ratio²	Relation to CpG island	Genomic region	Probe type	Prediction models³
cg01511567	SSRP1	chr11:57336157	0.19	Hypomethylation	− 0.0014	0.85	Shore	Promoter (< = 1 kb)	450 k	1³⁸
cg02872426	DDO	chr6:110415569	0.22	Hypomethylation	− 0.0048	2.35	Open sea	Promoter (< = 1 kb)	450 k	1³⁹
cg04084157	VGF	chr7:101165768	0.35	Hypermethylation	0.0010	0.24	Island	Promoter (< = 1 kb)	450 k	1³⁸
cg04528819	KLF14	chr7:130733488	0.22	Hypermethylation	0.0013	0.65	Island	Promoter (< = 1 kb)	450 k	2^38,40
cg06493994	SCGN	chr6:25652374	0.35	Hypermethylation	0.0016	0.40	Island	Promoter (< = 1 kb)	450 k	2³⁸
cg06639320	FHL2	chr2:105399282	0.70	Hypermethylation	0.0036	0.22	Island	Promoter (< = 1 kb)	450 k	8^{6,40,41,42,43,44,45,46,47,48}
cg06784991	ZYG11A	chr1:52843096	0.55	Hypermethylation	0.0039	0.42	Island	Promoter (< = 1 kb)	450 k	1³⁹
cg06874016	NKIRAS2	chr17:42025397	0.22	Hypomethylation	− 0.0010	0.51	Open sea	Distal promotor	450 k	1³⁹
cg07082267	No gene	chr16:85395429	0.25	Hypomethylation	− 0.0014	0.59	Open sea	Distal Intergenic	450 k	3^43,48,49
cg07553761	TRIM59	chr3:160450189	0.48	Hypermethylation	0.0035	0.52	Island	Promoter (< = 1 kb)	450 k	8^39–47
cg08262002	LDB2	chr4:16573700	0.45	Hypomethylation	− 0.0028	0.46	Open sea	Intron	450 k	1⁶
cg09809672	EDARADD	chr1:236394382	0.33	Hypomethylation	− 0.0028	0.78	Shore	Promoter (< = 1 kb)	450 k	5^{6,46,52,53,54}
cg13108341	DNAH9	chr17:11705394	0.33	Hypomethylation	− 0.0067	1.82	Open sea	Intron	EPIC850k	1⁵⁵
cg13552692	CCDC102B	chr18:68722210	0.54	Hypomethylation	− 0.0036	0.42	Open sea	Intron	EPIC850k	2^49,56
cg16054275	F5	chr1:169586784	0.36	Hypomethylation	− 0.0020	0.47	Open sea	Promoter (< = 1 kb)	450 k	1³⁹
cg16867657	ELOVL2	chr6:11044644	0.83	Hypermethylation	0.0061	0.17	Island	Promoter (< = 1 kb)	450 k	7^{39,54,55,57,58,59}
cg17268658	FHL2	chr2:105399288	0.62	Hypermethylation	0.0029	0.24	Island	Promoter (< = 1 kb)	EPIC850k	3^60,53,61
cg17372101	CNTNAP2	chr7:147803630	0.26	Hypomethylation	− 0.0019	0.75	Open sea	Intron	450 k	1⁶
cg21572722	ELOVL2	chr6:11044661	0.67	Hypermethylation	0.0029	0.19	Island	Promoter (< = 1 kb)	450 k	4^6,43,48,62
cg22736354	NHLRC1	chr6:18122488	0.46	Hypermethylation	0.0021	0.34	Island	Promoter (< = 1 kb)	450 k	1³⁸
cg22796704	ARHGAP22	chr10:48465491	0.27	Hypomethylation	− 0.0025	0.91	Shore	Intron	450 k	1⁶
cg24724428	ELOVL2	chr6:11044655	0.45	Hypermethylation	0.0047	0.78	Island	Promoter (< = 1 kb)	450 k	2^6,62
cg25410668	RPA2	chr1:27915066	0.43	Hypermethylation	0.0025	0.44	Shore	Promoter (< = 1 kb)	450 k	1³⁹

¹Slope of the mixed effects model.
²Ratio between the age estimate and the total variance.
³Number of forensic age prediction models that contains the CpG site.

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Table 1 Characteristics of the 23 forensic aDMPs in blood.

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