Figure 4

Visualization of critical brain regions for age prediction utilizing Grad CAM. (a) A global average attention map was created from the entire test set (n = 301). Regions marked with higher values, closer to red on the map, signify a greater contribution of those regions to age prediction. (b) A gender difference attention map was generated by subtracting the average attention map of female (n = 153) from that of male (n = 148). Regions marked with higher values, closer to red on the map, indicate stronger gender-specific influences of those regions on age prediction. All attention maps are overlaid over the averaged brain MR image from the test set.