Figure 2 | Scientific Reports

Figure 2

From: Association between copy number alterations estimated using low-pass whole genome sequencing of formalin-fixed paraffin-embedded prostate tumor tissue and cancer-specific clinical parameters

Figure 2

(A) Cohort-wide CNA frequency plotted for each 50 kb genomic bins. Well known PCa-specific recurrent alterations are marked. (B) Number of patients in our RP cohort with alterations in genes that were previously reported to be recurrently affected by CNA in early stage PCa and located in regions 8p, 8q, 13q, and 16q. The percent tumors with gains or losses observed across the entire cohort are shown for each gene against the bars. (C–F) Survival plots showing BCR-free survival probability for patients dichotomised based on the presence (Yes) or absence (No) of losses within 13q (C), 16q (D), and 8p (E), and gains within 8q (F). P-values are calculated from log-rank test.

Back to article page