Figure 3 | Scientific Reports

Figure 3

From: Association between copy number alterations estimated using low-pass whole genome sequencing of formalin-fixed paraffin-embedded prostate tumor tissue and cancer-specific clinical parameters

Figure 3

(A) Proportion of copy number gains and losses across all patients with CNA (n = 180) ranked according to their CNA burden. Curved dashed lines represent the smoothed conditional means calculated using the loess method. Vertical dashed lines represent the median (4.2%) and third quartile (9.35%) of the CNA burden. (B–E) Boxplots showing association between number of genomic losses and Gleason score (B), number of genomic gains and Gleason score (C), number of genomic losses and pathological T-stage (D), and number of genomic losses and surgical margin status (E). P-values are calculated from Kruskal–Wallis test (B–D) or Wilcoxon test (E). Inter, intermediate.

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