Figure 4 | Scientific Reports

Figure 4

From: Association between copy number alterations estimated using low-pass whole genome sequencing of formalin-fixed paraffin-embedded prostate tumor tissue and cancer-specific clinical parameters

Figure 4

(A) NMF clustering of patients based on copy number feature components. 3 distinct clusters were identified. (B) Contribution of different copy number feature components to the three signatures S1 (top), S2 (middle), and S3 (bottom). (C) Boxplot showing differences in genome instability as estimated using FGA between copy number signature groups. P-value from Wilcox test. (D) Survival plot showing differences in patient BCR-free survival based on copy number signature. P-value from log-rank test.

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