Figure 3 | Scientific Reports

Figure 3

From: The antihyperglycemic potential of pyrazolobenzothiazine 1, 1-dioxide novel derivative in mice using integrated molecular pharmacological approach

Figure 3

Kinetic study of α-glucosidase, data collected through in-vitro experiment was further analyze via GraphPad prism (A). (a)-Lineweaver–Burk plot of acarbose, (b)-Lineweaver–Burk plot for Compound S1, (c–e)-Assessment of Ki constant through slope versus inhibitor plot (S1 and acarbose respectively), (d–f)-Y of S1 and acarbose for the Assessment of Kiʹ constant through -intercept versus inhibitor plot (S1 and acarbose respectively). Kinetic study of α-amylase (B). (a)-Lineweaver–Burk plot of acarbose, (b)-Lineweaver–Burk plot for Compound S1, (c–e)-Assessment of Ki constant through slope versus inhibitor plot (S1 and acarbose respectively), (d–f)-Y of S1 and acarbose for the Assessment of Kiʹ constant through -intercept versus inhibitor plot (S1 and acarbose respectively).

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