Table 3 Oral bioavailability and drug-like properties of compound S1.

From: The antihyperglycemic potential of pyrazolobenzothiazine 1, 1-dioxide novel derivative in mice using integrated molecular pharmacological approach

Compound

Lipinski RO5

Egen rule

Veber rule

ADMET

GSK4/400 rule

S1

  1. Compounds fulfilled the criteria, ✕ couldn’t pass the criteria.