Figure 1 | Scientific Reports

Figure 1

From: Effects of different alkylating agents on photoreceptor degeneration and proliferative response of Müller glia

Figure 1

Dose-dependent photoreceptor degeneration after treatment with alkylating agents. TUNEL assay (red) in the non-treated control and the retinas treated with MNU-S (A), MNU-T (B), and MMS (C) at the given doses. Cross sections of the entire retinas and the higher magnifications of the central regions are shown. White arrowheads indicate TUNEL-negative areas, the length of which was quantitated and shown as graphs (D). Each bar represents the mean ± standard deviation (SD, n = 3). Cell nuclei are counterstained with DAPI (cyan). ONL outer nuclear layer, INL inner nuclear layer, GCL ganglion cell layer. Scale bars are 200 µm and 20 µm for lower and higher magnifications, respectively.

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