Figure 6
From: Evaluating sheep hemoglobins with MD simulations as an animal model for sickle cell disease
Correlation between center of mass distances between human 1ꞵ2-Val/Glu6 or sheep 1ꞵ2-Val/Glu5 and all other residues in chain 2ꞵ1, calculated from 1 to 2 μs, at every 50 ns, after standardization. Shown are the correlations between (a) HuHbA and HuHbS, (b) shHbB and HuHbS, (c) ShHbB and shHbS, (d) HuHbA and ShHbB, (e) HuHbA and shHbS, and (f) huHbS and shHbS, each with an inset consisting of the Pearson correlation coefficient (r), linear regression fitting (R2) and p-value (p).
