Figure 2
From: Environmental aluminum oxide inducing neurodegeneration in human neurovascular unit with immunity
Cerebral endothelial senescence caused by AlNP. (a) Immunostaining images validating endothelial senescence. ECs were treated with control medium (Con) or AlNPs at 1 ng/mL for 4 days showing (i) DNA damage, (ii, iii) cell-cycle arrest, (iv) senescence, and (v) functional impairment, respectively. (b) Quantitative analyses in bar graphs. Scale bars, 50 μm. All data are presented as mean ± SD measured by two-tailed unpaired Student’s t-test. *, p < 0.05 and ***, p < 0.001.
