Table 2 Clinicopathological characteristics of pan-trk IHC positive GIST.
Pan-trk IHC (−) | Pan-trk IHC (+) | P-value | |
|---|---|---|---|
n = 114 | n = 25 | ||
Age | 67.50 (41–88) | 64.00 (33–80) | 0.0609 |
Sex | 0.6628 | ||
Female | 49 | 12 | |
Male | 65 | 13 | |
Primary site | < 0.0001 | ||
Esophagus | 3 | 0 | |
Stomach | 103 | 0 | |
Duodenum | 0 | 16 | |
Small intestine | 7 | 9 | |
Vagina | 1 | 0 | |
Size (mm) | 0.3738 | ||
≦ 20 | 13 | 6 | |
21–50 | 54 | 11 | |
51–100 | 39 | 6 | |
> 100 | 8 | 2 | |
Mitotic figure | 0.1895 | ||
≦ 5 | 86 | 23 | |
6–10 | 15 | 1 | |
> 10 | 13 | 1 | |
Modified fletcher classification | 0.6583 | ||
Very low/low | 60 | 15 | |
Intermediate/high | 54 | 10 | |
MIB-1 index (%) | 0.432 | ||
< 10 | 85 | 22 | |
10–29 | 20 | 2 | |
≧ 30 | 9 | 1 | |
Imatinib treatment | n = 26 | n = 8 | 0.1456 |
Response | 19 | 3 | |
Non response | 3 | 3 | |
Unknown | 4 | 2 | |
