Figure 4 | Scientific Reports

Figure 4

From: Synthetic angiotensin II peptide derivatives confer protection against cerebral and severe non-cerebral malaria in murine models

Figure 4

Mice treated with Ang II and its synthetic peptide derivatives had low predictive score indicating low probability of developing ECM. Behavioral and functional analysis was performed 5 days post-infection in P. berghei ANKA-infected C57BL/6 mice treated with Ang II (red square), Ang II-SS (orange triangle), VIPF (blue inverted triangle), and the vehicle control group (black closed circle). The results are expressed as differences between values recorded before the infection and 5 days post-infection. Data are shown as mean ± SEM from a single experiment. ***P < 0.001, ****P < 0.0001, as determined by one-way ANOVA followed by Bonferroni’s multiple comparisons test compared to the vehicle control group, n = 7, except for the Ang II group where n = 8.

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