Table 9 Diagnostic performance comparison between proposed method and ophthalmologist. Accuracy, sensitivity, specificity, and AUC score obtained from the holdout test set. Values in parentheses represent improvements in performance between the proposed method and ophthalmologist diagnoses. The mean and standard deviation are obtained from the holdout test.

From: Enhancing foveal avascular zone analysis for Alzheimer’s diagnosis with AI segmentation and machine learning using multiple radiomic features

Method

Accuracy (%)

Sensitivity (%)

Specificity (%)

AUC (%)

Humans

53.1±15

52.8±14.1

53.7±18.8

53.2±21.0

Proposed

64.8±4.3\(^*\) (+ 11.7)

54.4±5.0\(^*\) (+ 1.6)

83.7±6.3\(^*\) (+ 30.0)

72.0±4.8\(^*\) (+ 18.8)

  1. * \(p<0.05\).