Table 1 Baseline demographic profiles and characteristics related to PegIFN response.
All patients (n = 650) | SR (n = 188) | Non-SR (n = 462) | p value | |
---|---|---|---|---|
Age (years) | 28.16 ± 0.26 | 26.65 ± 0.65 | 28.82 ± 0.32 | 0.000 |
Male gender | 469 | 132 (70.2%) | 340 (73.60%) | 0.370 |
Body weight | 63.77 ± 0.45 | 61.78 ± 0.80 | 64.50 ± 0.53 | 0.005 |
ALT (IU/mL) | 191.96 ± 5.43 | 209.6 ± 10.03 | 184.72 ± 6.43 | 0.037 |
HBV genotypes | ||||
B/ C | 242/402 | 92/95 | 147/310 | 0.000 |
D | 6 | 1 | 5 | – |
HBV-miR-3# | 5.77 ± 0.04 | 5.41 ± 0.09 | 5.91 ± 0.05 | 0.000 |
HBV pgRNA# | 6.13 ± 0.07 | 5.9 ± 0.13 | 6.2 ± 0.07 | 0.085 |
HBV DNA# | 7.94 ± 0.03 | 7.85 ± 0.05 | 8.0 ± 0.05 | 0.069 |
HBsAg# | 4.27 ± 0.02 | 4.16 ± 0.04 | 4.32 ± 0.03 | 0.001 |
HBeAg# | 3.02 ± 0.02 | 2.86 ± 0.04 | 3.08 ± 0.03 | 0.000 |
PegIFN-α 2a/2b | 221/429 | 57/131 | 164/298 | 0.207 |