Table 2 Logistic regression analyses of predictors for HBeAg seroconversion.

From: HBV-miR-3 is closely related to HBV replication and strongly predictive of HBeAg seroconversion in PegIFN-α treated patients

 

Univariate analyses

Multivariate analyses

OR

(95% CI)

p-value

OR

(95% CI)

p-value

0 W

 Male gender

1.186

0.817–1.722

0.370

0.833

0.502–1.383

0.480

 Genotypes

0.465

0.331–0.653

0.000

0.475

0.324–0.696

0.000

 Age

0.944

0.917–0.972

0.000

0.931

0.900–0.963

0.000

 Body weight

0.978

0.963–0.994

0.006

0.993

0.972–1.014

0.512

 ALT

1.001

1.000–1.002

0.040

1.002

1.000–1.003

0.011

 HBV-miR-3

0.686

0.590–0.798

0.000

0.641

0.511–0.805

0.000

 HBV pgRNA

0.408

0.832–1.011

0.000

1.004

0.885–1.139

0.951

 HBV DNA

0.810

0.657–1.017

0.050

1.265

0.860–1.861

0.233

 HBsAg

0.583

0.424–0.802

0.001

1.204

0.684–2.118

0.520

 HBeAg

0.475

0.348–0.649

0.000

0.451

0.304–0.668

0.000

12W

 Male gender

1.186

0.817 to1.722

0.370

1.224

0.700–2.142

0.478

 Genotypes

0.465

0.331–0.653

0.000

0.514

0.332–0.796

0.003

 Age

0.944

0.917–0.972

0.000

0.938

0.904–0.972

0.000

 Body weight

0.980

0.965–0.995

0.010

0.991

0.967–1.015

0.443

 ALT

0.999

0.997–1.001

0.212

1.002

0.999–1.004

0.140

 HBV-miR-3

0.440

0.365–0.531

0.000

0.548

0.431–0.697

0.000

 HBV pgRNA

0.720

0.664–0.781

0.000

0.012

0.738–0.963

0.012

 HBV DNA

0.642

0.578–0.712

0.000

1.202

0.940–1.536

0.143

 HBsAg

0.421

0.326–0.545

0.000

1.518

1.006–2.290

0.047

 HBeAg

0.402

0.332–0.486

0.000

0.419

0.298–0.590

0.000

24W

 Male gender

1.186

0.817–1.722

0.370

1.077

0.610–1.902

0.799

 Genotypes

0.465

0.331–0.653

0.000

0.667

0.424–1.048

0.079

 Age

0.944

0.917–0.972

0.000

0.939

0.905–0.974

0.001

 Body weight

0.982

0.966–0.997

0.023

1.002

0.978–1.027

0.862

 ALT

0.996

0.993–0.999

0.005

0.998

0.994–1.002

0.260

 HBV-miR-3

0.573

0.501–0.655

0.000

0.692

0.585–0.819

0.000

 HBV pgRNA

0.781

0.722–0.844

0.000

1.136

0.995–1.298

0.060

 HBV DNA

0.641

0.581–0.706

0.000

0.917

0.735–1.144

0.442

 HBsAg

0.512

0.420–0.624

0.000

1.162

0.861–1.568

0.326

 HBeAg

0.322

0.257–0.403

0.000

0.356

0.250–0.509

0.000