Table 2 Patient characteristics according to HER2 IHC categories.
From: A gene expression-based classifier for HER2-low breast cancer
Patient characteristics | HER2 IHC categories | Total | ||||||
|---|---|---|---|---|---|---|---|---|
HER2 0 | HER2-low | HER2 3+ | ||||||
n | % | n | % | n | % | n | % | |
Tumor size | ||||||||
≤ 2 cm | 13 | 12 | 42 | 26 | 10 | 31 | 65 | 21 |
2–5 cm | 44 | 40 | 83 | 51 | 19 | 59 | 146 | 48 |
> 5 cm | 53 | 48 | 34 | 21 | 3 | 9 | 90 | 30 |
Missing | 0 | 0 | 3 | 2 | 0 | 0 | 3 | 1 |
Grade | ||||||||
II | 36 | 33 | 86 | 53 | 9 | 28 | 131 | 43 |
III | 74 | 67 | 76 | 47 | 23 | 72 | 173 | 57 |
Hormone receptors | ||||||||
Positive | 31 | 28 | 119 | 73 | 20 | 63 | 170 | 56 |
Negative | 78 | 71 | 41 | 25 | 12 | 38 | 131 | 43 |
Missing | 1 | 1 | 2 | 1 | 0 | 0 | 3 | 1 |
PAM50 subtype* | ||||||||
Luminal A | 23 | 21 | 69 | 43 | 5 | 16 | 97 | 32 |
Luminal B | 18 | 16 | 27 | 17 | 2 | 6 | 47 | 15 |
HER2-enriched | 4 | 4 | 10 | 6 | 23 | 72 | 37 | 12 |
Basal-like | 56 | 51 | 36 | 22 | 1 | 3 | 93 | 31 |
Normal-like | 6 | 5 | 18 | 11 | 0 | 0 | 24 | 8 |
Undetermined | 3 | 3 | 2 | 1 | 1 | 3 | 6 | 2 |
Total | 110 | 100 | 162 | 100 | 32 | 100 | 304 | 100 |
