Figure 1 | Scientific Reports

Figure 1

From: Human amnion epithelial cell therapy reduces hypertension-induced vascular stiffening and cognitive impairment

Figure 1

Angiotensin II induced-hypertension and aortic stiffening is reduced by administration of amnion epithelial cells. (A) Immunostaining for HLA-G in angiotensin II and angiotensin II + amnion epithelial cell (AEC) treated mice. Nuclei were stained with haemotoxylin. 400X magnification, scale bar = 50 μm. Representative of n = 3. (B) Effect of amnion epithelial cells (AECs) on angiotensin II-induced hypertension (n = 8–11). All data are mean ± S.E.M. *P < 0.05. Two-way ANOVA with Tukey’s test. (C) Effect of angiotensin II infusion and co-treatment with AECs on pulse wave velocity (n = 6–7). All data are mean ± S.E.M. *P < 0.05. Two-way ANOVA with Sidak’s test. (D) Delta change (day 0 and 14) of pulse wave velocity (n = 6–7). All data are mean ± S.E.M. *P < 0.05. Student’s unpaired t-test.

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