Figure 2 | Scientific Reports

Figure 2

From: Human amnion epithelial cell therapy reduces hypertension-induced vascular stiffening and cognitive impairment

Figure 2

Administration of amnion epithelial cells prevents angiotensin II-induced aortic immune cell infiltration. (A) Representative flow cytometry dot plots showing gating strategy for total leukocytes (CD45+ high) from the aorta of mice infused with vehicle, angiotensin II, vehicle + amnion epithelial cells (AECs) and angiotensin II + AECs. The effect of angiotensin II infusion and co-treatment with AECs on (B) CD45+ leukocytes, (C) CD11b+ myeloid cells, (D) F4/80+ macrophages, (E) Ly6G+ neutrophils, (F) Ly6C+ low monocytes, (G) Ly6C+ high monocytes, (H) CD3+ T cells and (I) CD19+ B cells in the aorta (n = 8–11). All data are mean ± S.E.M. *P < 0.05. Two-way ANOVA with Sidak’s test.

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