Figure 4 | Scientific Reports

Figure 4

From: Human amnion epithelial cell therapy reduces hypertension-induced vascular stiffening and cognitive impairment

Figure 4

Administration of amnion epithelial cells improves angiotensin II-induced cognitive impairment. (A) Percentage of time spent in the inner zone in the open field test. (B) Total distance travelled (in cm) in the open field test (C) Representative heatmap plots showing interaction between familiar and novel objects in mice infused with vehicle, angiotensin II, vehicle + amnion epithelilal cells (AECs) and angiotensin II + AECs. (D) Effect of angiotensin II infusion and co-treatment of AECs on recognition memory (n = 7–9). All data are mean ± S.E.M. *P < 0.05. One-sample t-test versus 50%.

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