Table 2 List of genome-wide significant autosomal top hits from the meta-analysis.

From: Nuclear and mitochondrial genetic variants associated with mitochondrial DNA copy number

Chr

Position

Lead SNP

A1

A2

Freq A1a

Freq A1 (1000G)b

Effect

StdErr

Nearest gene

Distance BP

N

Best P-value

Proportion of variance explained by this SNP

Adjustment

6

135426558

rs4895440

t

a

0.2686

0.2773

0.0855

0.0118

HBS1L

50,522

16,130

3.39 × 10–13

0.0032

Age, sex, 4 PCs

17

38131187

rs56030650

a

c

0.4305

0.4573

− 0.0573

0.0105

GSDMA

0

16,130

4.85 × 10–08

0.0018

Age, sex, 4 PCs

  1. aFreq A1 = weighted average of frequency for allele 1 across all studies based on our meta-analysis results.
  2. bFreq A1 (1000G) = frequency of the A1 allele based on 1000 Genome Europeans.
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