Table 3 List of mitochondrial variants with p < 0.001 in the main model of the meta-analysis.

From: Nuclear and mitochondrial genetic variants associated with mitochondrial DNA copy number

Position

Freq

Freq (HelixMTdb)

Effect (main model)

StdErr (main model)

I2

N

P-value (main model)a,b

P-value (adjusted as main model + smoking)b

MT:9548_A

0.002

0.009

− 1.298

0.286

0

12

5.61 × 10–06

1.00 × 10–04

MT:13708_A

0.101

0.102

0.091

0.026

0

1880

4.72 × 10–04

1.12 × 10–02

MT:11719_A

0.500

0.590

0.053

0.016

0

8899

7.32 × 10–04

9.00 × 10–04

MT:73_G

0.520

0.612

0.053

0.016

0

8994

7.57 × 10–04

7.00 × 10–04

MT:15784_C

0.007

0.016

− 0.317

0.095

0

112

8.12 × 10–04

1.16 × 10–02

MT:12612_G

0.095

0.081

0.087

0.027

0

1779

1.08 × 10–03

1.23 × 10–02

  1. aMain model: adjusted for age, sex, 4 PCs.
  2. bP-values below 0.00016 (0.05/305) were considered significant. Bold font indicates significance.