Table 2 Information on the SNPs for the final screened KYN (n = 17).

SNP	Gene	Effect allele	Other allele	β	SE	P	P^a	F
rs10085935	IDO2	T	C	− 0.010	0.002	3.33E−09	0.365	17.30
rs10857319	FNIP2	T	C	− 0.009	0.002	9.45E−07	0.208	11.63
rs11646849	CDH13	A	G	− 0.009	0.002	6.40E−07	0.865	12.81
rs12082398	–	C	T	− 0.012	0.002	9.33E−07	0.545	11.55
rs12937634	ZNF652	C	T	0.008	0.002	2.28E−06	0.028	11.57
rs1426134	RP11-669M16.1	G	C	0.008	0.002	3.84E−06	0.664	10.61
rs1496635	LINC01791	C	A	0.009	0.002	2.12E−07	0.126	11.50
rs21327	NBPF13P	G	A	− 0.009	0.002	1.25E−07	0.766	11.39
rs2320536	MAML3	T	C	0.008	0.002	3.32E−06	0.432	11.02
rs2375475	RAVER2	T	C	− 0.008	0.002	1.41E−06	0.265	10.70
rs2491294	RP11-60A14.1	G	A	0.01	0.002	5.73E−07	0.132	10.71
rs4820242	CACN2	A	G	− 0.009	0.002	9.03E−07	0.578	11.79
rs6770323	SLC2A2	T	C	− 0.008	0.002	3.33E−06	0.890	10.87
rs6815057	MANBA	A	G	0.009	0.002	1.12E−06	0.169	12.21
rs7548008	CLDN19	G	A	− 0.016	0.004	3.56E−06	0.856	10.46
rs8051149	SLC7A5	A	G	0.026	0.003	9.07E−26	0.035	35.82
rs9857268	HSPE1P19	A	G	0.008	0.002	3.07E−06	0.358	10.73

SNP, single nucleotide polymorphism; Gene, Gene information is derived from Phenoscanner; β, effector value; SE, standard error; P^a, the P value of depression SNPs.

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