Table 1 Baseline characteristics according to statin therapy.

From: Benefits of statin therapy within a year after kidney transplantation

 

Statin (n = 414)

Control (n = 300)

p-value

Recipients

 Age, years

47.2 ± 10.7

43.4 ± 13.0

 < 0.001

 Male, n (%)

254 (61.4)

204 (68.0)

0.080

 Dialysis vintage, months

23.0 ± 37.7

26.1 ± 44.1

0.341

 Donor-specific antibodies, n (%)

29 (7.0)

19 (6.3)

0.840

 ABO incompatible KT, n (%)

76 (18.4)

64 (21.3)

0.372

Donors

 Deceased donor, n (%)

68 (16.4)

53 (17.7)

0.737

 Donor age, years

43.9 ± 11.7

44.6 ± 12.2

0.407

 Male donor, n (%)

206 (49.8)

137 (45.7)

0.315

 eGFR, mL/min/1.73m2

90.7 ± 27.0

91.1 ± 28.4

0.848

 Hypertension, n (%)

50 (12.1)

40 (13.3)

0.700

 Diabetes mellitus, n (%)

16 (3.9)

6 (2.0)

0.229

 Systolic blood pressure, mmHg

122.2 ± 15.7

119.9 ± 18.6

0.077

 Body mass index, kg/m2

23.8 ± 3.1

23.8 ± 3.0

0.981

Recipient cardiovascular risk factors

 Body mass index, kg/m2

23.3 ± 3.6

22.1 ± 3.3

 < 0.001

 Hypertension, n (%)

385 (93.0)

275 (91.7)

0.604

 Waist-hip ratio

0.9 ± 0.1

0.9 ± 0.1

0.686

 Diabetes mellitus, n (%)

118 (28.5)

64 (21.3)

0.037

 MACE prior to KT, n (%)

43 (10.4)

20 (6.7)

0.113

 Statin use prior to KT, n (%)

173 (41.8)

50 (16.7)

 < 0.001

 LDL-cholesterol, mg/dL

88.6 ± 33.1

76.5 ± 28.1

 < 0.001

 HDL-cholesterol, mg/dL

44.9 ± 15.6

46.0 ± 17.7

0.383

 Total cholesterol, mg/dL

163.0 ± 43.4

144.4 ± 38.6

 < 0.001

 Recipient smoking, n (%)

0.743

  Current

26 (6.3)

21 (7.0)

 

  Former

170 (41.1%)

115 (38.3)

 

 Systolic blood pressure, mmHg

138.1 ± 18.5

135.7 ± 19.1

0.081

  1. Data are presented as number (percentage) or mean ± standard deviation.
  2. eGFR estimated glomerular filtration rate, HDL high-density lipoprotein, MACE major adverse cardiovascular event, KT kidney transplantation, LDL low-density lipoprotein.