Table 1 Demographic, clinical characteristics, baseline osteoporosis risk factors, biochemistry, interventions, and outcomes by study completion status.

From: A pilot feasibility randomised controlled trial of bone antiresorptive agents on bone turnover markers in critically ill women

Variable

All

Number

18

Age (yrs)

68.8 ± 7.5

BMI (kg/m2)

29.6 ± 6.1

Osteoporosis risk factors

 Parent hip fracture

1 (6)

 Previous fragility fracture

0 (0)

 BMI < 20 (kg/m2)

0 (0)

 Rheumatoid arthritis

0 (0)

 Alcohol > 3 units/day

0 (0)

 Smoker

2 (11)

 Secondary osteoporosis

18 (100)

 Glucocorticoids

0 (0)

 Anti-fracture agents

0 (0)

Chronic disease

 None

16 (89)

 Respiratory

1 (6)

 Cardiovascular

0 (0)

 Liver

0 (0)

Immunosuppressed

 Apache III score

57.8 ± 25.2

ICU admission category

 Surgical

4 (22)

 Medical

7 (39)

 Cardiothoracic

7 (39)

Interventions

 Mechanical ventilation

15 (83)

 Ventilation duration (days)

3.9 [1.7, 8.6]

 Glucocorticoid

5 (28)

 CRRT

2 (11)

Outcomes

 ICU LOS (days)

8.5 [60, 15.5]

 Hospital LOS (days)

20.6 ± 11.6

 ICU survival

18 (100)

 Hospital survival

18 (100)

  1. Data are shown as mean (± standard deviation), median [interquartile range] or number (%).
  2. BMI body mass index, APACHE acute physiology and chronic health evaluation; CRRT continuous renal replacement therapy, LOS length of stay.