Table 9 Fluorouracil (FLU) and sericin/propolis/fluorouracil nanoparticles (NF) concentration in rats’ plasma as affected by time intervals.

From: In vitro and in vivo anti-colorectal cancer effect of the newly synthesized sericin/propolis/fluorouracil nanoplatform through modulation of PI3K/AKT/mTOR pathway

Time (h)

FLU (ug/ml)

nSE/PRO/FLU (ug/ml)

0

0.0

0.0

0.2

20.0

10.0

0.5

35.0

16.0

1

66.0

18.0

2

52.0

22.0

4

41.0

40.0

6

22.0

55.0

8.0

10.0

22.0

12.0

2.0

12.0

24.0

0.0

5.0