Figure 6 | Scientific Reports

Figure 6

From: MICAL2 implies immunosuppressive features and acts as an independent and adverse prognostic biomarker in pancreatic cancer

Figure 6

Involvement of MICAL2 in the immune microenvironment of pancreatic cancer. (A) Comparison of the infiltration rate of 22 immune cells between patients in the high and low MICAL2 expression group. (B) The correlation between MIACL2 expression and immune score (high MICAL2 expression group: 89, low expression MICAL2 group: 89). (C) The correlation between MICAL2 expression and CD8 + T cell infiltration. (D) The correlation between MICAL2 expression and M2 Macrophage infiltration. (E) The correlation analysis between MICAL2 and CD163. (F) Representative immunohistochemical images of MICAL2 and CD163 in pancreatic cancer samples (scale bar 100 μm). (G) Differential analysis of CD163-positive cell counts grouped by MICAL2 in our cohort (high MICAL2 expression group: 72, low expression MICAL2 group: 112) (*p < 0.05).

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