Table 1 Participant demographics and baseline alcohol craving and consumption.

From: Psilocybin-induced changes in neural reactivity to alcohol and emotional cues in patients with alcohol use disorder: an fMRI pilot study

 

Psilocybin

Placebo

Baseline group differences

Sample size (male/female)

5 (4/1)

6 (3/3)

χ2(1) = 1.06; p = 0.30

Race/ethnicity

White (4)

Hispanic (1)

White (4)

Hispanic (1)

Black (1)

χ2(2) = 0.917; p = 0.63

Annual income

$97,500 ($54,237)

Range: 25–150 K

$148,333 ($109,025)

Range: 50–360 K

t(8) = 0.85, p = 0.42

Age, years

48.80 (10.52)

Range: 35–63

44.00 (12.62)

Range: 27–59

t(9) = − 0.68; p = 0.52

Weight (lbs)

201.00 (34.70)

Range: 160–256

159.67 (49.36)

Range: 112–246

t(9) = − 1.57; p = 0.15

Cravinga

16.00 (6.44)

Range: 8–23

14.67 (3.72)

Range: 8–19

t(9) = − 0.43; p = 0.68

PHDDb

17.86 (17.50)

Range: 0–39.29

14.29 (17.35)

Range: 0–42.86

t(9) = − 0.34; p = 0.74

DPDb

2.58 (0.73)

Range: 1.37–3.30

1.31 (1.64)

Range: 0–4.18

t(9) = − 1.60; p = 0.15

PDDb

77.14 (17.05)

Range: 60.71–96.43

29.17 (33.61)

Range: 0–89.29

t(9) = − 2.88; p = 0.02*

fMRI FD

0.13 (0.03)

Range: 0.10–0.18

0.12 (0.02)

Range: 0.09–0.13

t(9) = − 1.14; p = 0.28

  1. Reported as means, (standard deviations), and ranges; aPenn Alcohol Craving Scale; bTimeline Follow Back (TLFB); PHDD: percent heavy drinking days; DPD: drinks per day; PDD: percent drinking days; FD: framewise displacement *p < 0.05.
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