Figure 4 | Scientific Reports

Figure 4

From: NDUFS7 variant in dogs with Leigh syndrome and its functional validation in a Drosophila melanogaster model

Figure 4

Cryosections from the biceps femoris muscle of case 1. (A) H&E, (B) modified Gomori trichrome, (C). mitochondrial specific reactions cytochrome C oxidase (COX), and (D) combined cytochrome C oxidase and succinic dehydrogenase (SDH). Variability in myofiber size was present in A and B without obvious ragged red fibers. Punctate dark brown intramyofiber deposits highlighted by the COX and combined COX and SDH reactions indicating mitochondrial accumulations are indicated with arrows.

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