Figure 6 | Scientific Reports

Figure 6

From: NDUFS7 variant in dogs with Leigh syndrome and its functional validation in a Drosophila melanogaster model

Figure 6

Influence of wildtype or mutant transgene overexpression in ND-20 knockdown lines. Percentages of dark pupae in all unhatched pupae are shown. Chi-square tests were used to determine statistical differences between different lines. KD-OE-MUT showed impaired development compared to the KD ND-20, while the KD-OE-WT line showed improved development, but still complete lethality before eclosion upon ubiquitous dosage manipulation. The numerical values for counted pupae and flies are provided in Table S5.

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