Figure 9

Primase inhibition assay performed with the selected compounds. Bar diagram signifying inhibition of LdmtPRI1 by (A) Benfotiamine and (B) Capecitabine. (C) Dose response inhibition plot of LdmtPRI1 by benfotiamine (IC50 20.68 ± 0.03 nM), Capecitabine (IC50 15.27 ± 0.03 nM).