Figure 4 | Scientific Reports

Figure 4

From: Amphetamine increases vascular permeability by modulating endothelial actin cytoskeleton and NO synthase via PAR-1 and VEGF-R

Figure 4

DAM mediated actin cytoskeleton rearrangement in HCMECs. F-actin and nuclei staining 5 and 50min after addition of 1mM DAM. (A) Untreated control, (B) 1mM DAM, (C) 10µM ML161 treatment and (D) 20µM Y-27632 treatment prior to DAM addition. (E) Quantification of the relative cell surface areas. Single asterisks indicate comparison to untreated control. Brackets indicate comparisons between experimental groups. n=3. *p<0.05, **p < 0.01, ***p < 0.001.

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