Figure 3

Protectivity of the CSFV/PCV2 bivalent vaccine against virus replication. (a) Schema of the experimental design of pig studies. VC and NC groups were challenged with CSFV while VP and NP groups were challenged with PCV2 four weeks after 1st vaccination. Black circle indicated the time of blood collection. Viral loads in serum (b and c) and various organ (d and e) samples were evaluated by quantitative PCR. The data are presented as mean ± SEM (n = 5 per group). Statistical significance between Vaccine and Non-vaccine groups: ^***p < 0.001. Abbreviations: HLN, hilar (trachea-bronchial) lymph nodes; ILN, inguinal lymph nodes; IV, ileocecal valve; MLN, mesenteric lymph nodes; VC & NC, vaccinated and non-vaccinated pigs challenged with CSFV; VP & NP, vaccinated and non-vaccinated pigs challenged with PCV2.