Table 1 Lesion scores of tissues from vaccinated and non-vaccinated SPF pigs in CSFV/PCV2 challenge studies.

From: Efficacy evaluation of a bivalent subunit vaccine against classical swine fever virus and porcine circovirus type 2

 

VC

NC

VP

NP

Brain

0.00 ± 0.00

2.20 ± 0.20+++

0.13 ± 0.10

0.00 ± 0.00

Tonsil

0.00 ± 0.00

2.00 ± 0.00+++

0.83 ± 0.06

0.77 ± 0.07

Lung

0.00 ± 0.00

1.60 ± 0.24+++

1.07 ± 0.24

2.47 ± 0.40***

Spleen

0.00 ± 0.00

1.40 ± 0.24+++

0.70 ± 0.17

1.43 ± 0.24***

HLN

0.00 ± 0.00

2.20 ± 0.20+++

0.53 ± 0.16

1.43 ± 0.24***

MLN

0.00 ± 0.00

1.80 ± 0.37+++

0.43 ± 0.08

1.10 ± 0.04***

ILN

0.00 ± 0.00

2.40 ± 0.51+++

0.73 ± 0.12

1.33 ± 0.05***

IV

0.00 ± 0.00

1.80 ± 0.37+++

0.23 ± 0.08

0.47 ± 0.12**

  1. Lesions were scored from 0 (normal) to 4 (most severe) and presented as mean ± SEM (n = 5 per group). The vaccine groups were compared with their non-vaccinated counterparts, and statistical significance are presented as follows: +++p < 0.001 (CSFV challenge study); **p < 0.01 and ***p < 0.001 (PCV2 challenge study). Abbreviations: HLN, hilar (trachea-bronchial) lymph nodes; ILN, inguinal lymph nodes; IV, ileocecal valve; MLN, mesenteric lymph nodes; VC & NC, vaccinated and non-vaccinated pigs challenged with CSFV; VP & NP, vaccinated and non-vaccinated pigs challenged with PCV2.
Back to article page