Figure 4

Correlation network analysis of gut and pharyngeal microbiota in cynomolgus macaques. The correlation network constructed based on the SPARCC method represents the relationship of bacterial species in the (a) gut and (b) pharyngeal microbiota of macaques (r > 0.3, P < 0.05). The colors of the edges represent correlation types: positive (red) and negative (blue) correlation. The nodes were designated as pie charts indicating the relative abundance of each bacterium in macaques with different TB stages: negative control (blue), latent (yellow) and active (red).