Figure 3 | Scientific Reports

Figure 3

From: Genome-wide identification of fitness-genes in aminoglycoside-resistant Escherichia coli during antibiotic stress

Figure 3

Competition between deletion mutants and parental strains with and without STREP (700 mg/L), GEN (50 mg/L) or NEO (1000 mg/L). The relative richness of deletion mutants after a 24-h co-culture experiment with STREP (a), GEN (b) or NEO (c) resistant parental strains are shown. Two sets of conditions are depicted: control conditions (dark turquoise/dark blue/dark red) and exposure with 700 mg/L STREP, 50 mg/L GEN or 1000 mg/L NEO (light turquoise/light brown/light red). Each mixture sample initially included the same concentration of KO-mutants and parental strains. The relative richness was calculated by sample sequencing and an in-house in silico analysis pipeline (detailed in “Method”). The figure was depicted with GraphPad Prism 9 (GraphPad Software, San Diego, USA).

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