Table 4 Clinicopathological characteristics of 8 cases in AFP-H group.

From: High serum alpha-fetoprotein and positive immunohistochemistry of alpha-fetoprotein are related to poor prognosis of gastric cancer with liver metastasis

Age

Sex

AFP* (ng/ml)

Size (mm)

pT

pN

ly

v

Histology

IHC**

AFP

GPC3

SALL4

74

F

44,613

100

2

0

1

1

tub2

+

+

+

80

M

368.8

65

2

2

1

1

por1

+

+

+

68

M

254.1

60

2

0

1

1

tub2

+

+

+

81

M

172.1

78

2

1

0

3

tub2

+

+

+

84

M

49.5

90

3

2

1

1

tub2

+

+

+

85

M

28.1

70

2

1

0

2

por1

+

+

+

68

M

20.7

53

1

0

1

2

tub1

+

+

+

55

F

20.7

40

1

0

3

2

por2

−

−

+

  1. A positive status was observed when cytoplasmic staining for AFP and GPC3 was observed in 1% or more, and nuclear staining for SALL4 was observed in 10% or more.
  2. Samples from patients with AFP-H group showed immunohistochemical features of GAPEP, and all AFP-positive specimens were immunohistochemically positive for both GPC3 and SALL4.
  3. *Preoperative serum AFP.
  4. **Immunohistochemical staining.
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