Table 1 Absolute body weights in rats dosed with CeO2 NPs for 90 days (unit: g). Data are represented as mean ± SD.
Day | Male | Female | ||||||
|---|---|---|---|---|---|---|---|---|
Control | 10 mg/kg/day | 100 mg/kg/day | 1000 mg/kg/day | Control | 10 mg/kg/day | 100 mg/kg/day | 1000 mg/kg/day | |
1 | 220.0 ± 7.23 | 221.5 ± 6.66 | 221.3 ± 5.84 | 223.0 ± 7.74 | 175.7 ± 11.00 | 175.5 ± 9.21 | 180.6 ± 8.74 | 177.2 ± 9.11 |
8 | 294.9 ± 9.73 | 292.1 ± 9.47 | 289.7 ± 11.91 | 288.6 ± 12.08 | 205.7 ± 13.78 | 204.6 ± 13.63 | 206.8 ± 12.69 | 202.4 ± 10.92 |
15 | 348.0 ± 21.40 | 340.4 ± 19.24 | 344.1 ± 21.08 | 339.0 ± 21.13 | 232.6 ± 16.55 | 231.1 ± 18.95 | 233.6 ± 17.60 | 226.4 ± 12.58 |
22 | 399.9 ± 23.00 | 397.6 ± 18.65 | 388.2 ± 27.34 | 389.2 ± 21.39 | 255.4 ± 19.92 | 248.2 ± 22.76 | 255.2 ± 16.91 | 247.4 ± 16.41 |
29 | 436.5 ± 29.75 | 436.5 ± 21.47 | 421.7 ± 30.51 | 421.1 ± 25.35 | 268.1 ± 25.58 | 264.3 ± 23.58 | 271.5 ± 21.13 | 264.8 ± 20.37 |
36 | 467.7 ± 31.88 | 468.7 ± 24.54 | 453.9 ± 36.32 | 448.2 ± 26.45 | 283.9 ± 23.94 | 275.0 ± 24.98 | 282.9 ± 23.70 | 274.2 ± 23.17 |
43 | 492.2 ± 36.34 | 497.8 ± 29.97 | 478.9 ± 41.90 | 477.1 ± 28.33 | 295.2 ± 24.51 | 290.7 ± 25.27 | 295.1 ± 26.12 | 283.6 ± 21.11 |
50 | 520.7 ± 41.31 | 522.0 ± 31.26 | 502.7 ± 44.75 | 496.5 ± 29.52 | 302.3 ± 26.82 | 294.5 ± 29.88 | 307.1 ± 29.69 | 294.2 ± 27.99 |
57 | 539.2 ± 44.40 | 539.4 ± 33.60 | 520.3 ± 49.10 | 513.2 ± 33.57 | 306.9 ± 31.32 | 300.8 ± 27.43 | 312.9 ± 24.80 | 304.4 ± 27.23 |
64 | 560.8 ± 47.59 | 562.3 ± 38.01 | 540.4 ± 51.20 | 530.6 ± 32.81 | 317.8 ± 30.38 | 307.5 ± 27.71 | 322.3 ± 29.35 | 307.8 ± 28.83 |
71 | 574.7 ± 51.22 | 576.4 ± 45.17 | 552.1 ± 53.18 | 545.9 ± 33.69 | 324.4 ± 29.41 | 318.0 ± 31.24 | 328.6 ± 32.12 | 312.8 ± 26.86 |
78 | 589.9 ± 52.39 | 594.6 ± 45.86 | 567.9 ± 54.03 | 561.0 ± 35.45 | 330.1 ± 32.74 | 321.9 ± 32.77 | 333.3 ± 29.92 | 320.8 ± 31.34 |
85 | 604.2 ± 54.23 | 607.3 ± 45.12 | 577.4 ± 54.36 | 573.4 ± 35.87 | 333.3 ± 33.92 | 324.3 ± 31.62 | 338.8 ± 30.50 | 328.0 ± 32.56 |
91 | 613.1 ± 54.04 | 617.5 ± 46.38 | 584.1 ± 57.15 | 580.0 ± 35.10 | 340.9 ± 30.61 | 331.6 ± 30.94 | 348.3 ± 31.37 | 329.2 ± 26.72 |
