Table 2 Changes in food consumption after treatment with CeO2 NPs during the test period (unit: g). Data are represented as mean ± SD.

From: Safety assessment and gastrointestinal retention of orally administered cerium oxide nanoparticles in rats

Day

Male

Female

Control

10 mg/kg/day

100 mg/kg/day

1000 mg/kg/day

Control

10 mg/kg/day

100 mg/kg/day

1000 mg/kg/day

8

31.1 ± 1.22

31.6 ± 0.40

31.6 ± 2.43

32.0 ± 1.56

22.7 ± 0.69

22.2 ± 1.45

22.1 ± 0.69

22.3 ± 0.87

15

34.2 ± 1.53

33.4 ± 1.88

34.2 ± 2.68

34.2 ± 2.20

24.7 ± 1.13

23.6 ± 2.38

24.0 ± 0.71

23.7 ± 1.10

22

35.9 ± 1.11

35.7 ± 0.88

33.9 ± 2.23

37.0 ± 3.37

25.5 ± 1.36

23.9 ± 1.61

24.5 ± 0.58

25.2 ± 1.33

29

36.0 ± 1.48

35.9 ± 1.03

33.4 ± 2.82*

34.9 ± 3.07

25.4 ± 1.72

25.1 ± 1.12

25.1 ± 0.43

25.8 ± 1.72

36

35.2 ± 1.34

36.4 ± 1.56

34.3 ± 2.86

34.4 ± 2.43

25.7 ± 1.44

24.4 ± 1.22

25.2 ± 0.85

25.4 ± 1.01

43

35.8 ± 1.46

36.5 ± 1.52

34.4 ± 2.95

35.5 ± 1.81

25.5 ± 1.80

24.9 ± 1.69

25.4 ± 0.24

25.6 ± 1.51

50

35.8 ± 2.74

35.7 ± 1.65

34.0 ± 2.97

35.5 ± 1.90

25.0 ± 1.32

24.4 ± 1.64

25.3 ± 0.62

26.0 ± 1.55

57

35.3 ± 2.04

35.6 ± 1.76

33.8 ± 2.78

35.2 ± 1.74

24.5 ± 1.55

24.0 ± 1.88

24.2 ± 0.47

25.3 ± 1.44

64

35.2 ± 2.45

3.51 ± 1.56

33.6 ± 3.48

34.4 ± 1.72

24.2 ± 1.39

23.3 ± 0.94

24.4 ± 1.11

24.4 ± 0.94

71

38.1 ± 1.84

37.6 ± 1.98

35.8 ± 3.37

37.2 ± 1.95

25.3 ± 2.97

25.9 ± 2.49

27.1 ± 0.79

26.9 ± 2.08

78

38.4 ± 2.24

37.7 ± 1.81

36.0 ± 3.11

38.0 ± 2.33

26.9 ± 1.06

25.6 ± 2.53

26.7 ± 1.08

26.7 ± 1.63

85

36.9 ± 1.81

36.7 ± 1.34

34.5 ± 3.73

35.8 ± 1.66

25.6 ± 0.80

24.1 ± 2.14

25.2 ± 0.46

25.7 ± 1.56

91

35.4 ± 1.49

35.9 ± 1.02

33.3 ± 3.71

34.7 ± 1.80

25.0 ± 1.36

24.3 ± 2.82

26.1 ± 0.67

25.0 ± 0.87

  1. * Significant differences from control group (p < 0.05).
Back to article page