Table 4 Results of clinical chemistry analysis after treating CeO₂ NPs for 90 days. Data are represented as mean ± SD.

GLU

(mg/dL)

108.4 ± 16.25

101.9 ± 13.76

108.3 ± 26.23

108.0 ± 20.98

118.4 ± 15.70

114.5 ± 20.98

124.3 ± 29.65

115.2 ± 27.54

BUN

(mg/dL)

16.8 ± 1.76

19.0 ± 2.62

17.0 ± 2.01

16.7 ± 0.79

21.3 ± 3.65

20.4 ± 3.17

20.3 ± 3.39

20.5 ± 0.056

CREA

(mg/dL)

0.40 ± 0.017

0.41 ± 0.28

0.41 ± 0.033

0.41 ± 0.036

0.53 ± 0.061

0.49 ± 0.046

0.47 ± 0.046

0.50 ± 0.056

TP

(g/dL)

6.43 ± 0.288

6.35 ± 0.295

6.55 ± 0.358

6.38 ± 0.326

7.03 ± 0.359

7.15 ± 0.272

7.55 ± 0.484*

7.18 ± 0.449

ALB

(g/dL)

4.17 ± 0.221

4.11 ± 0.239

4.34 ± 0.230

4.19 ± 0.127

5.07 ± 0.253

5.09 ± 0.253

5.47 ± 0.354

5.06 ± 0.546

A/G

(ratio)

1.87 ± 0.247

1.85 ± 0.182

1.97 ± 0.191

1.96 ± 0.368

2.61 ± 0.270

2.54 ± 0.525

2.64 ± 0.225

2.44 ± 0.525

AST

(IU/L)

103.3 ± 10.87

122.8 ± 15.31

110.7 ± 19.03

114.5 ± 21.95

112.2 ± 22.86

118.1 ± 19.22

108.2 ± 20.02

113.3 ± 12.42

ALT

(IU/L)

29.0 ± 6.04

29.0 ± 4.05

30.4 ± 4.58

26.8 ± 3.73

24.9 ± 4.55

30.7 ± 15.24

36.2 ± 13.53

30.0 ± 8.97

TBIL

(mg/dL)

0.099 ± 0.0200

0.093 ± 0.0077

0.108 ± 0.089

0.098 ± 0.0129

0.135 ± 0.0155

0.140 ± 0.0220

0.139 ± 0.0265

0.139 ± 0.0211

GGT

(IU/L)

0.32 ± 0.225

0.54 ± 0.186

0.67 ± 1.184

0.26 ± 0.243

0.68 ± 0.377

0.68 ± 0.294

0.50 ± 0.279

0.70 ± 0.387

ALP

(IU/L)

256.3 ± 48.25

288.7 ± 66.22

252.3 ± 30.64

251.0 ± 43.47

161.0 ± 32.27

164.2 ± 61.28

157.6 ± 54.31

162.1 ± 77.41

TCHO

(mg/dL)

70.9 ± 13.46

72.6 ± 15.20

80.7 ± 22.07

68.5 ± 7.34

72.9 ± 11.54

74.6 ± 15.31

79.7 ± 9.44

84.2 ± 18.23

TG

(mg/dL)

38.6 ± 12.99

39.2 ± 16.67

36.0 ± 16.51

33.6 ± 9.29

27.2 ± 18.04

25.3 ± 9.34

29.2 ± 10.72

21.2 ± 11.24

Ca

(mg/dL)

10.36 ± 0.322

10.37 ± 0.322

10.74 ± 0.602

10.48 ± 0.335

10.95 ± 0.454

10.99 ± 0.264

11.52 ± 0.315*

11.39 ± 0.743

IP

(mg/dL)

8.41 ± 0.923

8.61 ± 0.950

8.72 ± 0.748

8.31 ± 0.855

7.29 ± 0.590

7.30 ± 0.970

7.73 ± 1.028

7.70 ± 1.506

K

(mmol/L)

8.17 ± 1.717

8.09 ± 1.466

8.20 ± 1.072

7.99 ± 1.621

6.76 ± 0.950

7.07 ± 0.688

7.33 ± 0.457

7.40 ± 0.678

CK

(IU/L)

611.0 ± 128.60

753.6 ± 197.12

577.1 ± 103.23

681.3 ± 296.47

575.4 ± 168.58

590.4 ± 197.78

425.6 ± 149.18

525.8 ± 140.50

PL

(mg/dL)

99.0 ± 15.27

101.0 ± 17.65

108.2 ± 24.85

97.0 ± 6.82

135.8 ± 17.31

138.0 ± 21.03

146.5 ± 17.10

145.3 ± 29.60

Na

(mmol/L)

141.8 ± 1.32

142.8 ± 1.32

143.5 ± 1.58*

144.2 ± 1.69 + 

144.3 ± 1.34

144.4 ± 1.26

145.3 ± 1.06

144.6 ± 3.31

Cl

(mmol/L)

101.8 ± 0.92

102.7 ± 1.70

102.6 ± 1.17

104.2 ± 1.48 + 

104.4 ± 0.97

104.7 ± 1.34

105.3 ± 1.64

105.6 ± 2.88