Table 6 Relative organ weights after CeO₂ NPs treatment at 10, 100 and 1000 mg/kg/day for 90 days. Data are represented as mean ± SD.

Adrenal glands

0.0117 ± 0.00160

0.0115 ± 0.00187

0.0110 ± 0.00171

0.0121 ± 0.00174

0.0269 ± 0.00436

0.0255 ± 0.00320

0.0261 ± 0.00406

0.0264 ± 0.00659

Brain

0.3729 ± 0.03729

0.3824 ± 0.03504

0.4007 ± 0.03353

0.4015 ± 0.02103

0.6526 ± 0.0569

0.6812 ± 0.05664

0.6549 ± 0.06734

0.6679 ± 0.04506

Heart

0.2929 ± 0.02405

0.3082 ± 0.02809

0.3041 ± 0.01882

0.3007 ± 0.01810

0.3496 ± 0.01025

0.3527 ± 0.02700

0.3377 ± 0.02761

0.3467 ± 0.02291

Kidneys

0.6898 ± 0.05300

0.7050 ± 0.06246

0.7258 ± 0.06819

0.7393 ± 0.06153

0.7038 ± 0.06160

0.7172 ± 0.08006

0.7393 ± 0.06358

0.7624 ± 0.04956

Liver

2.8513 ± 0.25879

2.7856 ± 0.18070

2.7986 ± 0.18963

2.8362 ± 0.13656

2.7878 ± 0.15186

2.7518 ± 0.17018

2.8912 ± 0.30323

2.8847 ± 0.14370

Spleen

0.1712 ± 0.02525

0.1787 ± 0.01831

0.1585 ± 0.02835

0.1668 ± 0.01923

0.1921 ± 0.02619

0.1840 ± 0.01888

0.1996 ± 0.02826

0.1929 ± 0.01696

Thymus

0.0749 ± 0.01415

0.0731 ± 0.01228

0.0640 ± 0.00814

0.0740 ± 0.01323

0.0937 ± 0.01539

0.1046 ± 0.01866

0.1100 ± 0.01783

0.1131 ± 0.01330

Thyroid and parathyroid glands

0.0047 ± 0.00065

0.0055 ± 0.00087

0.0053 ± 0.00102

0.0053 ± 0.00120

0.0070 ± 0.00127

0.0084 ± 0.00126

0.0079 ± 0.00155

0.0074 ± 0.00118

Lung

0.3204 ± 0.02631

0.3497 ± 0.05824

0.3315 ± 0.03233

0.3290 ± 0.01874

0.4402 ± 0.01580

0.4558 ± 0.02690

0.4362 ± 0.04385

0.4572 ± 0.05995

Testes

0.6037 ± 0.06395

0.6287 ± 0.06835

0.6679 ± 0.06823

0.6513 ± 0.02851

–

–

–

–

Ovaries

–

–

–

–

0.0311 ± 0.00393

0.0341 ± 0.00831

0.314 ± 0.00838

0.0360 ± 0.00665

Uterus/cervix

–

–

–

–

0.2505 ± 0.05985

0.2587 ± 0.09123

0.2499 ± 0.08202

0.2302 ± 0.06139