Figure 1 | Scientific Reports

Figure 1

From: Elucidating Hedgehog pathway's role in HNSCC progression: insights from a 6-gene signature

Figure 1

Hedgehog pathway was overactive in HNSCC and associated with prognosis and metabolism. (A) Hedgehog pathway enrichment scores for normal and tumor samples in the TCGA-HNSC cohort. (B) Hedgehog pathway enrichment scores for the two age groups grouped with a cutoff of 60 years. (C) Differences in Hedgehog pathway enrichment scores between male and female samples. (D) Hedgehog pathway activity between the four stages. (E) Hedgehog pathway activity of different grade. (F) Kaplan–Meier curves for samples plotted based on Hedgehog pathway scores.

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