Table 3 Docking scores of the top five drugs with LPAR (1, 3, and 6) protein structures using the DockThor server.
LPAR1 | LPAR3 | LPAR6 | |||
|---|---|---|---|---|---|
Drug | Score (kcal/mol) | Drug | Score (kcal/mol) | Drug | Score (kcal/mol) |
Ki16425 (reference compound) | − 8.701 | Ki16425 (reference compound) | − 8.186 | Xanthenylacetic acid (reference compound) | − 8.216 |
Lupron | − 10.817 | Nilotinib | − 10.343 | Bromocriptine | − 10.394 |
Telmisatran | − 9.42 | Neflamapimod | − 9.81 | Lupron | − 10.392 |
CORT108297 | − 9.275 | Telmisartan | − 9.598 | Nilotinib | − 10.296 |
Nilotinib | − 9.243 | Montelukast | − 9.401 | Brexpiparazole | − 10.249 |
Bromocriptine | − 9.232 | CORT108297 | − 9.369 | Telmisartan | − 10.105 |
