Figure 1 | Scientific Reports

Figure 1

From: Prefrontal theta—gamma transcranial alternating current stimulation improves non-declarative visuomotor learning in older adults

Figure 1

Study design. In this triple-blinded, placebo-controlled, parallel-group research study, participants came to the clinic for 19 appointments. The first appointment included history taking, implementation of the Montreal Cognitive Assessment (MoCA), and an initial administration of the Alternating Serial Reaction Time (ASRT) task (outlined in red). At each of the subsequent 16 appointments, participants received 20 min of active or sham tACS treatment bilaterally targeting the dorsolateral prefrontal cortex (F3/F4, according to the international 10–20 system) while completing Computerized Cognitive Training (CCT) based on the n-back paradigm on a tablet (outlined in blue). After completion of treatment, two further appointments were held to examine direct treatment effects and long-term effects (outlined in green), separated by a 3-month break (outlined in yellow).

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