Figure 3
miR-let7a, miR-29a and miR-720 are dysregulated in patients with acute pulmonary embolism. The three promising miRNAs were validated in a bigger patient cohort (n = 177) by qPCR. (a) miR-let7a was found to be significantly decreased, (b) miR-29a to be significantly increased and (c) miR-720 to be significantly decreased in patients with pulmonary embolism (PE).; Data is shown as normalized expression to cel-miR-39 ± SEM; **p ≤ 0.01; ***p ≤ 0.001; Student´s t-test of patients with PE and specific sex- and age-matched healthy controls.
